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KMID : 0351619720130010097
Kyungpook Medical Journal
1972 Volume.13 No. 1 p.97 ~ p.103
Effects of Cold Exposure and Whole-Body X-Irradiation on the Level of Protein in Some Organs in the Mouse
˩ܼðÔ/Kang, Byung Jo
ì°ßÓü¤/ì°ÔÔìé/ì°ùÓôÊ/ì°Ðñà¸/Lee, Sang Hwa/Lee, Dong Il/Rhee, Han Chul/Lee, Ki Suk
Abstract
In an attempt to observe the possible radioprotective action of the low temperature in mammals, the albino mouse was subjected to cold exposure at -10.3C, whole-body, ~: irradiation :with 900r, and the X-irradiation :Following the cold exposure for one hour.
The levels cf protein of the liver, brain and heart were measured at 1/2, i and 3 hours after the cold exposure and/or the ~:-irradiation. and the results -ere compared witlT the control, i. e. , non-irradiated and non-cold exposes animal.
Protein was measured by the method described by Lowry et al.
The results obtained are summarized as folio~.vs:
1. The level of protein in the live~~, brain and heart of the normal mouse was 101.13 17.57, 62.79=6.89 and 87.086.68mg/gm wet wt. respectively.
2. The protein content of the liver in. the X-irradiated group showed a tendency of increase comparing with the controh though there was a slight decrease at 2 hours post-irradiation.
In the groups where the cold exposure alone or the combination of the cold exposure and
X-irradiation were applied, there vas no significant change from the control.
3. The protein content of the brain immediately after the X-irradiation produced no change from the control, but a slight increase was ncted at three hours post-irradiation after a slight decrease at ~ hours post-irradiation. In the cold exposure group, there was a general tendency of decrease throughout the experiment. When the cold exposure and X-irradiation were combined, there was a tendency of increase in the protein content comparing from the control.
4. The protein content of the heart iri the X-irradiated group showed a tendency of increase throughout the experiment, with the exception of decrease at ~ hours post-irradiation. In the groups where the cold exposure alone or the combination of the cold exposure and X-irradiation were applied, a tendency of decrease in the protein content was observed from the control.
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